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Broadly Cross-Reactive, Nonneutralizing Antibodies against Influenza B Virus Hemagglutinin Demonstrate Effector Function-Dependent Protection against Lethal Viral Challenge in Mice

Protection from influenza virus infection is canonically associated with antibodies that neutralize the virus by blocking the interaction between the viral hemagglutinin and host cell receptors. However, protection can also be conferred by other mechanisms, including antibody-mediated effector funct...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Asthagiri Arunkumar, Guha, Ioannou, Andriani, Wohlbold, Teddy John, Meade, Philip, Aslam, Sadaf, Amanat, Fatima, Ayllon, Juan, García-Sastre, Adolfo, Krammer, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401450/
https://ncbi.nlm.nih.gov/pubmed/30626682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01696-18
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