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Cross-reactive antibodies binding to H4 hemagglutinin protect against a lethal H4N6 influenza virus challenge in the mouse model

Influenza viruses of the H4 subtype are widespread in wild birds, circulate in domestic poultry, readily infect mammals, and tolerate the insertion of a polybasic cleavage site. In addition, serological evidence suggests that humans working with poultry are exposed to these viruses. While H4 viruses...

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Vydáno v:Emerg Microbes Infect
Hlavní autoři: Amanat, Fatima, Meade, Philip, Strohmeier, Shirin, Krammer, Florian
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455122/
https://ncbi.nlm.nih.gov/pubmed/30866770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2018.1564369
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