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Hepatic STAT3 inhibition amplifies the inflammatory response in obese mice during sepsis

The purpose of this study was to better understand the role obesity plays in the inflammatory response during sepsis, specifically regarding the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway in the liver. We hypothesized that inhibiting STAT3 would lead to an inc...

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Detalles Bibliográficos
Publicado en:Am J Physiol Endocrinol Metab
Main Authors: Williamson, Lauren, Ayalon, Itay, Shen, Hui, Kaplan, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397363/
https://ncbi.nlm.nih.gov/pubmed/30576248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00341.2018
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