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High Fat Diet-Induced Obesity Increases Myocardial Injury and Alters Cardiac STAT3 Signaling in Mice after Polymicrobial Sepsis

Little is known about how obesity affects the heart during sepsis and we sought to investigate the obesity-induced cardiac effects that occur during polymicrobial sepsis. Six-week old C57BL/6 mice were randomized to a high fat (HFD) (60% kcal fat) or normal diet (ND) (16% kcal fat). After 6 wks of f...

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Vydáno v:Biochim Biophys Acta
Hlavní autoři: DeMartini, Theodore, Nowell, Marchele, James, Jeanne, Williamson, Lauren, Lahni, Patrick, Shen, Hui, Kaplan, Jennifer M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653424/
https://ncbi.nlm.nih.gov/pubmed/28625915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.06.008
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