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High Fat Diet-Induced Obesity Increases Myocardial Injury and Alters Cardiac STAT3 Signaling in Mice after Polymicrobial Sepsis

Little is known about how obesity affects the heart during sepsis and we sought to investigate the obesity-induced cardiac effects that occur during polymicrobial sepsis. Six-week old C57BL/6 mice were randomized to a high fat (HFD) (60% kcal fat) or normal diet (ND) (16% kcal fat). After 6 wks of f...

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Bibliografiset tiedot
Julkaisussa:Biochim Biophys Acta
Päätekijät: DeMartini, Theodore, Nowell, Marchele, James, Jeanne, Williamson, Lauren, Lahni, Patrick, Shen, Hui, Kaplan, Jennifer M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653424/
https://ncbi.nlm.nih.gov/pubmed/28625915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.06.008
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