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Hepatic STAT3 inhibition amplifies the inflammatory response in obese mice during sepsis

The purpose of this study was to better understand the role obesity plays in the inflammatory response during sepsis, specifically regarding the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway in the liver. We hypothesized that inhibiting STAT3 would lead to an inc...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Williamson, Lauren, Ayalon, Itay, Shen, Hui, Kaplan, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397363/
https://ncbi.nlm.nih.gov/pubmed/30576248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00341.2018
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