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Arginase Inhibition Ameliorates Hepatic Metabolic Abnormalities in Obese Mice

OBJECTIVES: We examined whether arginase inhibition influences hepatic metabolic pathways and whole body adiposity in diet-induced obesity. METHODS AND RESULTS: After obesity induction by a high fat diet (HFD), mice were fed either the HFD or the HFD with an arginase inhibitor, N(ω)-hydroxy-nor-L-ar...

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Main Authors: Moon, Jiyoung, Do, Hyun Ju, Cho, Yoonsu, Shin, Min-Jeong
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109998/
https://ncbi.nlm.nih.gov/pubmed/25057910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103048
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