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Transgene-associated human growth hormone expression in pancreatic β-cells impairs identification of sex-based gene expression differences
Fluorescent protein reporter genes are widely used to identify and sort murine pancreatic β-cells. In this study, we compared use of the MIP-GFP transgene, which exhibits aberrant expression of human growth hormone (hGH), with a newly derived Ins2(Apple) allele that lacks hGH expression on the expre...
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| Pubblicato in: | Am J Physiol Endocrinol Metab |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6397359/ https://ncbi.nlm.nih.gov/pubmed/30532991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00229.2018 |
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