Transgenic expression of the human growth hormone minigene promotes pancreatic β-cell proliferation

Transgenic mouse models are designed to study the role of specific proteins. To increase transgene expression the human growth hormone (hGH) minigene, including introns, has been included in many transgenic constructs. Until recently, it was thought that the hGH gene was not spliced, transcribed, an...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Baan, Mieke, Kibbe, Carly R., Bushkofsky, Justin R., Harris, Ted W., Sherman, Dawn S., Davis, Dawn Belt
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Rapid Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631542/
https://ncbi.nlm.nih.gov/pubmed/26202070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00244.2015
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