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Development of a human antibody cocktail that deploys multiple functions to confer pan-ebolavirus protection

Passive administration of monoclonal antibodies (mAbs) is a promising therapeutic approach for Ebola virus disease (EVD). However, all mAbs and mAb cocktails that have entered clinical development are specific for a single member of the Ebolavirus genus, Ebola virus (EBOV), and ineffective against o...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Host Microbe
Egile Nagusiak: Wec, Anna Z., Bornholdt, Zachary A., He, Shihua, Herbert, Andrew S., Goodwin, Eileen, Wirchnianski, Ariel S., Gunn, Bronwyn M., Zhang, Zirui, Zhu, Wenjun, Liu, Guodong, Abelson, Dafna M., Moyer, Crystal L., Jangra, Rohit K., James, Rebekah M., Bakken, Russell R., Bohorova, Natasha, Bohorov, Ognian, Kim, Do H., Pauly, Michael H., Velasco, Jesus, Bortz, Robert H., Whaley, Kevin J., Goldstein, Tracey, Anthony, Simon J., Alter, Galit, Walker, Laura M., Dye, John M., Zeitlin, Larry, Qiu, Xiangguo, Chandran, Kartik
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6396299/
https://ncbi.nlm.nih.gov/pubmed/30629917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.12.004
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