A two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates

Recent and ongoing outbreaks of Ebola virus disease (EVD) underscore the unpredictable nature of ebolavirus reemergence and the urgent need for antiviral treatments. Unfortunately, available experimental vaccines and immunotherapeutics are specific for a single member of the Ebolavirus genus, Ebola...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Bornholdt, Zachary A., Herbert, Andrew S., Mire, Chad E., He, Shihua, Cross, Robert W., Wec, Anna Z., Abelson, Dafna M., Geisbert, Joan B., James, Rebekah M., Rahim, Md Niaz, Zhu, Wenjun, Borisevich, Viktoriya, Banadyga, Logan, Gunn, Bronwyn M., Agans, Krystle N., Wirchnianski, Ariel S., Goodwin, Eileen, Tierney, Kevin, Shestowsky, William S., Bohorov, Ognian, Bohorova, Natasha, Velasco, Jesus, Ailor, Eric, Kim, Do, Pauly, Michael H., Whaley, Kevin J., Alter, Galit, Walker, Laura M., Chandran, Kartik, Zeitlin, Larry, Qiu, Xiangguo, Geisbert, Thomas W., Dye, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341996/
https://ncbi.nlm.nih.gov/pubmed/30629918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.12.005
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