Metabolic regulation of T cell development by Sin1–mTORC2 is mediated by pyruvate kinase M2

Glucose metabolism plays a key role in thymocyte development. The mammalian target of rapamycin complex 2 (mTORC2) is a critical regulator of cell growth and metabolism, but its role in early thymocyte development and metabolism has not been fully studied. We show here that genetic ablation of Sin1,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Mol Cell Biol
मुख्य लेखकों: Ouyang, Xinxing, Han, Yuheng, Qu, Guojun, Li, Man, Wu, Ningbo, Liu, Hongzhi, Arojo, Omotooke, Sun, Hongxiang, Liu, Xiaobo, Liu, Dou, Chen, Lei, Zou, Qiang, Su, Bing
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2018
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6392101/
https://ncbi.nlm.nih.gov/pubmed/30428057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjy065
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