ADAMTS-9 in Mouse Cartilage Has Aggrecanase Activity That Is Distinct from ADAMTS-4 and ADAMTS-5

A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-4 and ADAMTS-5 are the principal aggrecanases in mice and humans; however, mice lacking the catalytic domain of both enzymes (TS-4/5∆cat) have no skeletal phenotype, suggesting there is an alternative aggrecanase for modulating...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Rogerson, Fraser M., Last, Karena, Golub, Suzanne B., Gauci, Stephanie J., Stanton, Heather, Bell, Katrina M., Fosang, Amanda J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387038/
https://ncbi.nlm.nih.gov/pubmed/30699963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030573
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