Cargando...
A human post-catalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation
During exon ligation, the S. cerevisiae spliceosome recognizes the 3´-splice site (3´SS) of precursor mRNA through non-Watson-Crick pairing with the 5´SS and the branch adenosine, in a conformation stabilised by Prp18 and Prp8. Here we present the 3.3 Å cryoEM structure of a human post-catalytic spl...
Guardado en:
| Publicado en: | Science |
|---|---|
| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6386133/ https://ncbi.nlm.nih.gov/pubmed/30705154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw5569 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|