FoxO Transcription Factors Are Critical Regulators of Diabetes-Related Muscle Atrophy

Insulin deficiency and uncontrolled diabetes lead to a catabolic state with decreased muscle strength, contributing to disease-related morbidity. FoxO transcription factors are suppressed by insulin and thus are key mediators of insulin action. To study their role in diabetic muscle wasting, we crea...

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Detalles Bibliográficos
Publicado en:Diabetes
Autores principales: O’Neill, Brian T., Bhardwaj, Gourav, Penniman, Christie M., Krumpoch, Megan T., Suarez Beltran, Pablo A., Klaus, Katherine, Poro, Kennedy, Li, Mengyao, Pan, Hui, Dreyfuss, Jonathan M., Nair, K. Sreekumaran, Kahn, C. Ronald
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2019
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385751/
https://ncbi.nlm.nih.gov/pubmed/30523026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0416
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