FoxO Transcription Factors Are Critical Regulators of Diabetes-Related Muscle Atrophy

Insulin deficiency and uncontrolled diabetes lead to a catabolic state with decreased muscle strength, contributing to disease-related morbidity. FoxO transcription factors are suppressed by insulin and thus are key mediators of insulin action. To study their role in diabetic muscle wasting, we crea...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: O’Neill, Brian T., Bhardwaj, Gourav, Penniman, Christie M., Krumpoch, Megan T., Suarez Beltran, Pablo A., Klaus, Katherine, Poro, Kennedy, Li, Mengyao, Pan, Hui, Dreyfuss, Jonathan M., Nair, K. Sreekumaran, Kahn, C. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2019
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385751/
https://ncbi.nlm.nih.gov/pubmed/30523026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0416
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