Loss of FoxOs in muscle reveals sex-based differences in insulin sensitivity but mitigates diet-induced obesity

OBJECTIVE: Gender influences obesity-related complications, including diabetes. Females are more protected from insulin resistance after diet-induced obesity, which may be related to fat accumulation and muscle insulin sensitivity. FoxOs regulate muscle atrophy and are targets of insulin action, but...

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Pubblicato in:Mol Metab
Autori principali: Penniman, Christie M., Suarez Beltran, Pablo A., Bhardwaj, Gourav, Junck, Taylor L., Jena, Jayashree, Poro, Kennedy, Hirshman, Michael F., Goodyear, Laurie J., O'Neill, Brian T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819874/
https://ncbi.nlm.nih.gov/pubmed/31767172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.10.001
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