O-GlcNAc Regulates FoxO Activation in Response to Glucose

FoxO proteins are key transcriptional regulators of nutrient homeostasis and stress response. The transcription factor FoxO1 activates expression of gluconeogenic, including phosphoenolpyruvate carboxykinase and glucose-6-phosphatase, and also activates the expression of the oxidative stress respons...

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Main Authors: Housley, Michael P., Rodgers, Joseph T., Udeshi, Namrata D., Kelly, Timothy J., Shabanowitz, Jeffrey, Hunt, Donald F., Puigserver, Pere, Hart, Gerald W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Mechanisms of Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423255/
https://ncbi.nlm.nih.gov/pubmed/18420577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802240200
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