O-GlcNAc Regulates FoxO Activation in Response to Glucose

FoxO proteins are key transcriptional regulators of nutrient homeostasis and stress response. The transcription factor FoxO1 activates expression of gluconeogenic, including phosphoenolpyruvate carboxykinase and glucose-6-phosphatase, and also activates the expression of the oxidative stress respons...

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Bibliographic Details
Main Authors: Housley, Michael P., Rodgers, Joseph T., Udeshi, Namrata D., Kelly, Timothy J., Shabanowitz, Jeffrey, Hunt, Donald F., Puigserver, Pere, Hart, Gerald W.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423255/
https://ncbi.nlm.nih.gov/pubmed/18420577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802240200
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