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O-GlcNAc Transferase Regulates Mitotic Chromatin Dynamics

Mitosis must faithfully divide the genome such that each progeny inherits the same genetic material. DNA condensation is crucial in ensuring that chromosomes are correctly attached to the mitotic spindle for segregation, preventing DNA breaks or constrictions from the contractile ring. Histones form...

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Autores principales: Sakabe, Kaoru, Hart, Gerald W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966060/
https://ncbi.nlm.nih.gov/pubmed/20805223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.158170
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