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Gambogic acid triggers vacuolization-associated cell death in cancer cells via disruption of thiol proteostasis
Gambogic acid (GA), a xanthonoid extracted from the resin of the tree, Garcinia hanburyi, was recently shown to exert anticancer activity in multiple studies, but the underlying action mechanism remains unclear. Here, we show that GA induces cancer cell death accompanied by vacuolation in vitro and...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6385239/ https://ncbi.nlm.nih.gov/pubmed/30796201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1360-4 |
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