A carregar...

Intracellular crowding by age-dependent neuromelanin accumulation disrupts neuronal proteostasis and triggers Parkinson disease pathology

In Parkinson disease (PD), there is a preferential degeneration of neurons that contain the dark-brown cytoplasmic pigment neuromelanin, in particular dopaminergic neurons of the substantia nigra (SN), the loss of which leads to the typical motor symptoms of the disease and constitutes the cardinal...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Vila, Miquel, Laguna, Ariadna, Carballo-Carbajal, Iria
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844506/
https://ncbi.nlm.nih.gov/pubmed/31480882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1659621
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!