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Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS

Superoxide dismutase-1 (SOD1) maturation comprises a string of posttranslational modifications which transform the nascent peptide into a stable and active enzyme. The successive folding, metal ion binding, and disulphide acquisition steps in this pathway can be catalysed through a direct interactio...

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Vydáno v:PLoS Biol
Hlavní autoři: Sala, Fernanda A., Wright, Gareth S. A., Antonyuk, Svetlana V., Garratt, Richard C., Hasnain, S. Samar
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383938/
https://ncbi.nlm.nih.gov/pubmed/30735496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000141
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