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Import, Maturation, and Function of SOD1 and Its Copper Chaperone CCS in the Mitochondrial Intermembrane Space

Cu,Zn, superoxide dismutase (SOD1) is a ubiquitous enzyme localized in multiple cellular compartments, including mitochondria, where it concentrates in the intermembrane space (IMS). Similar to other small IMS proteins, the import and retention of SOD1 in the IMS is linked to its folding and maturat...

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Bibliografiske detaljer
Main Authors: Kawamata, Hibiki, Manfredi, Giovanni
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962758/
https://ncbi.nlm.nih.gov/pubmed/20367259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3212
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