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Import, Maturation, and Function of SOD1 and Its Copper Chaperone CCS in the Mitochondrial Intermembrane Space

Cu,Zn, superoxide dismutase (SOD1) is a ubiquitous enzyme localized in multiple cellular compartments, including mitochondria, where it concentrates in the intermembrane space (IMS). Similar to other small IMS proteins, the import and retention of SOD1 in the IMS is linked to its folding and maturat...

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Библиографические подробности
Главные авторы: Kawamata, Hibiki, Manfredi, Giovanni
Формат: Artigo
Язык:Inglês
Опубликовано: Mary Ann Liebert, Inc. 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962758/
https://ncbi.nlm.nih.gov/pubmed/20367259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3212
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