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Oxygen-induced maturation of SOD1: a key role for disulfide formation by the copper chaperone CCS
The antioxidant enzyme Cu,Zn-superoxide dismutase (SOD1) has the distinction of being one of the most abundant disulfide-containing protein known in the eukaryotic cytosol; however, neither catalytic nor physiological roles for the conserved disulfide are known. Here we show that the disulfide statu...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1150991/ https://ncbi.nlm.nih.gov/pubmed/15215895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600276 |
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