The deubiquitinating enzyme Usp14 controls ciliogenesis and Hedgehog signaling

Primary cilia are hair-like organelles that play crucial roles in vertebrate development, organogenesis and when dysfunctional result in pleiotropic human genetic disorders called ciliopathies, characterized by overlapping phenotypes, such as renal and hepatic cysts, skeletal defects, retinal degene...

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Publicado en:Hum Mol Genet
Autores principales: Massa, Filomena, Tammaro, Roberta, Prado, Miguel A, Cesana, Marcella, Lee, Byung-Hoon, Finley, Daniel, Franco, Brunella, Morleo, Manuela
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
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General Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381316/
https://ncbi.nlm.nih.gov/pubmed/30388222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy380
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