The deubiquitinating enzyme Usp14 controls ciliogenesis and Hedgehog signaling

Primary cilia are hair-like organelles that play crucial roles in vertebrate development, organogenesis and when dysfunctional result in pleiotropic human genetic disorders called ciliopathies, characterized by overlapping phenotypes, such as renal and hepatic cysts, skeletal defects, retinal degene...

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Bibliografske podrobnosti
izdano v:Hum Mol Genet
Main Authors: Massa, Filomena, Tammaro, Roberta, Prado, Miguel A, Cesana, Marcella, Lee, Byung-Hoon, Finley, Daniel, Franco, Brunella, Morleo, Manuela
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
General Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381316/
https://ncbi.nlm.nih.gov/pubmed/30388222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy380
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