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HIF1α deubiquitination by USP8 is essential for ciliogenesis in normoxia
Loss of primary cilia is a key feature of von Hippel-Lindau tumor suppressor (VHL)-associated pathology. Although VHL-deficiency predisposes cells to precipitous cilia disassembly in response to growth factor cues, it does not affect ciliogenesis. Here, using a siRNA-based screen to find genes that...
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| Publicat a: | EMBO Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BlackWell Publishing Ltd
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303451/ https://ncbi.nlm.nih.gov/pubmed/24378640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201337688 |
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