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The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43
Connexin-43 (Cx43, also known as GJA1) is the most ubiquitously expressed connexin isoform in mammalian tissues. It forms intercellular gap junction (GJ) channels, enabling adjacent cells to communicate both electrically and metabolically. Cx43 is a short-lived protein which can be quickly degraded...
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| Publicado no: | J Biol Chem |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5971442/ https://ncbi.nlm.nih.gov/pubmed/29626091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001315 |
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