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Extracellular and intracellular cleavages of proBDNF required at two distinct stages of late-phase LTP

Although late-phase long-term potentiation (L-LTP) is implicated in long-term memory, its molecular mechanisms are largely unknown. Here we provide evidence that L-LTP can be divided into two stages: an induction stage (I) and a maintenance stage (II). Both stages require mature brain-derived neurot...

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Pubblicato in:NPJ Sci Learn
Autori principali: Pang, Petti T, Nagappan, Guhan, Guo, Wei, Lu, Bai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380376/
https://ncbi.nlm.nih.gov/pubmed/30792890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjscilearn.2016.3
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