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Role of pro-brain-derived neurotrophic factor (proBDNF) to mature BDNF conversion in activity-dependent competition at developing neuromuscular synapses

Formation of specific neuronal connections often involves competition between adjacent axons, leading to stabilization of the active terminal, while retraction of the less active ones. The underlying molecular mechanisms remain unknown. We show that activity-dependent conversion of pro–brain-derived...

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Autori principali: Je, H. Shawn, Yang, Feng, Ji, Yuanyuan, Nagappan, Guhan, Hempstead, Barbara L., Lu, Bai
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465384/
https://ncbi.nlm.nih.gov/pubmed/23019376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207767109
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