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Role of pro-brain-derived neurotrophic factor (proBDNF) to mature BDNF conversion in activity-dependent competition at developing neuromuscular synapses

Formation of specific neuronal connections often involves competition between adjacent axons, leading to stabilization of the active terminal, while retraction of the less active ones. The underlying molecular mechanisms remain unknown. We show that activity-dependent conversion of pro–brain-derived...

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Autors principals: Je, H. Shawn, Yang, Feng, Ji, Yuanyuan, Nagappan, Guhan, Hempstead, Barbara L., Lu, Bai
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465384/
https://ncbi.nlm.nih.gov/pubmed/23019376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207767109
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