Cleavage of proBDNF to BDNF by a Tolloid-Like Metalloproteinase Is Required for Acquisition of In Vitro Eyeblink Classical Conditioning

The tolloid/bone morphogenetic protein-1 family of metalloproteinases have an important role in the regulation of embryonic pattern formation and tissue morphogenesis. Studies suggest that they participate in mechanisms of synaptic plasticity in adults, but very little is known about their function....

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Main Authors: Keifer, Joyce, Sabirzhanov, Boris E., Zheng, Zhaoqing, Li, Wei, Clark, Timothy G.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2009
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825740/
https://ncbi.nlm.nih.gov/pubmed/19940191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3649-09.2009
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