Φορτώνει......
Autophagy induced by SAHA affects mutant P53 degradation and cancer cell survival
Missense mutations in the TP53 gene produce mutant p53 (mutp53) proteins which may acquire oncogenic properties favoring chemoresistance, cell migration, and metastasis. The exploitation of cellular pathways that promote mutp53 degradation may reduce cell proliferation and invasion as well as increa...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Biosci Rep |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Portland Press Ltd.
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6379511/ https://ncbi.nlm.nih.gov/pubmed/30745455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20181345 |
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