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Transcriptional Functionality of Germ Line p53 Mutants Influences Cancer Phenotype

PURPOSE: The TP53 tumor suppressor gene encodes a sequence-specific transcription factor that is able to transactivate several sets of genes, the promoters of which include appropriate response elements. Although human cancers frequently contain mutated p53, the alleles as well as the clinical expre...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Monti, Paola, Ciribilli, Yari, Jordan, Jennifer, Menichini, Paola, Umbach, David M., Resnick, Michael A., Luzzatto, Lucio, Inga, Alberto, Fronza, Gilberto
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128783/
https://ncbi.nlm.nih.gov/pubmed/17606709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-06-2545
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