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WW Domain-Containing Proteins YAP and TAZ in the Hippo Pathway as Key Regulators in Stemness Maintenance, Tissue Homeostasis, and Tumorigenesis

The Hippo pathway is a conserved signaling pathway originally defined in Drosophila melanogaster two decades ago. Deregulation of the Hippo pathway leads to significant overgrowth in phenotypes and ultimately initiation of tumorigenesis in various tissues. The major WW domain proteins in the Hippo p...

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Bibliografski detalji
Izdano u:Front Oncol
Glavni autori: Chen, Yu-An, Lu, Chen-Yu, Cheng, Tian-You, Pan, Szu-Hua, Chen, Hsin-Fu, Chang, Nan-Shan
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378284/
https://ncbi.nlm.nih.gov/pubmed/30805310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00060
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