WW Domain-Containing Proteins YAP and TAZ in the Hippo Pathway as Key Regulators in Stemness Maintenance, Tissue Homeostasis, and Tumorigenesis

The Hippo pathway is a conserved signaling pathway originally defined in Drosophila melanogaster two decades ago. Deregulation of the Hippo pathway leads to significant overgrowth in phenotypes and ultimately initiation of tumorigenesis in various tissues. The major WW domain proteins in the Hippo p...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Oncol
Egile Nagusiak: Chen, Yu-An, Lu, Chen-Yu, Cheng, Tian-You, Pan, Szu-Hua, Chen, Hsin-Fu, Chang, Nan-Shan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Oncology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378284/
https://ncbi.nlm.nih.gov/pubmed/30805310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00060
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