TRPA1 mediates the antinociceptive properties of the constituent of Crocus sativus L., safranal

Safranal, contained in Crocus sativus L., exerts anti‐inflammatory and analgesic effects. However, the underlying mechanisms for such effects are poorly understood. We explored whether safranal targets the transient receptor potential ankyrin 1 (TRPA1) channel, which in nociceptors mediates pain sig...

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Publicado en:J Cell Mol Med
Autores principales: Li Puma, Simone, Landini, Lorenzo, Macedo, Sergio J., Seravalli, Viola, Marone, Ilaria M., Coppi, Elisabetta, Patacchini, Riccardo, Geppetti, Pierangelo, Materazzi, Serena, Nassini, Romina, De Logu, Francesco
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378183/
https://ncbi.nlm.nih.gov/pubmed/30636360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14099
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