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Experimental and computational analyses reveal dynamics of tumor vessel cooption and optimal treatment strategies

Cooption of the host vasculature is a strategy that some cancers use to sustain tumor progression without—or before—angiogenesis or in response to antiangiogenic therapy. Facilitated by certain growth factors, cooption can mediate tumor infiltration and confer resistance to antiangiogenic drugs. Unf...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Voutouri, Chrysovalantis, Kirkpatrick, Nathaniel D., Chung, Euiheon, Mpekris, Fotios, Baish, James W., Munn, Lance L., Fukumura, Dai, Stylianopoulos, Triantafyllos, Jain, Rakesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377457/
https://ncbi.nlm.nih.gov/pubmed/30700544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818322116
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