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Pirfenidone normalizes the tumor microenvironment to improve chemotherapy

Normalization of the tumor microenvironment by selectively targeting components of the tumor extracellular matrix has been recently proposed to have the potential to decompress tumor blood vessels, increase vessel perfusion and thus, improve drug delivery and the efficacy of cancer therapy. Therefor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Polydorou, Christiana, Mpekris, Fotios, Papageorgis, Panagiotis, Voutouri, Chrysovalantis, Stylianopoulos, Triantafyllos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421866/
https://ncbi.nlm.nih.gov/pubmed/28445938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15534
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