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Scaling rules for diffusive drug delivery in tumor and normal tissues
Delivery of blood-borne molecules and nanoparticles from the vasculature to cells in the tissue differs dramatically between tumor and normal tissues due to differences in their vascular architectures. Here we show that two simple measures of vascular geometry—δ(max) and λ—readily obtained from vasc...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033252/ https://ncbi.nlm.nih.gov/pubmed/21224417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018154108 |
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