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Scaling rules for diffusive drug delivery in tumor and normal tissues
Delivery of blood-borne molecules and nanoparticles from the vasculature to cells in the tissue differs dramatically between tumor and normal tissues due to differences in their vascular architectures. Here we show that two simple measures of vascular geometry—δ(max) and λ—readily obtained from vasc...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033252/ https://ncbi.nlm.nih.gov/pubmed/21224417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018154108 |
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