Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

The blood vessels of cancerous tumours are leaky(1–3) and poorly organized(4–7). This can increase the interstitial fluid pressure (IFP) inside tumours and reduce blood supply to them, which impairs drug delivery(8–9). Anti-angiogenic therapies – which “normalize” the abnormal blood vessels in tumou...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Chauhan, Vikash P., Stylianopoulos, Triantafyllos, Martin, John D., Popović, Zoran, Chen, Ou, Kamoun, Walid S., Bawendi, Moungi G., Fukumura, Dai, Jain, Rakesh K.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370066/
https://ncbi.nlm.nih.gov/pubmed/22484912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nnano.2012.45
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires