Multistage nanoparticle delivery system for deep penetration into tumor tissue

Current Food and Drug Administration-approved cancer nanotherapeutics, which passively accumulate around leaky regions of the tumor vasculature because of an enhanced permeation and retention (EPR) effect, have provided only modest survival benefits. This suboptimal outcome is likely due to physiolo...

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Autors principals: Wong, Cliff, Stylianopoulos, Triantafyllos, Cui, Jian, Martin, John, Chauhan, Vikash P., Jiang, Wen, Popović, Zoran, Jain, Rakesh K., Bawendi, Moungi G., Fukumura, Dai
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038705/
https://ncbi.nlm.nih.gov/pubmed/21245339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018382108
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