Multistage nanoparticle delivery system for deep penetration into tumor tissue

Current Food and Drug Administration-approved cancer nanotherapeutics, which passively accumulate around leaky regions of the tumor vasculature because of an enhanced permeation and retention (EPR) effect, have provided only modest survival benefits. This suboptimal outcome is likely due to physiolo...

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Detalles Bibliográficos
Autores principales: Wong, Cliff, Stylianopoulos, Triantafyllos, Cui, Jian, Martin, John, Chauhan, Vikash P., Jiang, Wen, Popović, Zoran, Jain, Rakesh K., Bawendi, Moungi G., Fukumura, Dai
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038705/
https://ncbi.nlm.nih.gov/pubmed/21245339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018382108
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