Multistage nanoparticle delivery system for deep penetration into tumor tissue

Current Food and Drug Administration-approved cancer nanotherapeutics, which passively accumulate around leaky regions of the tumor vasculature because of an enhanced permeation and retention (EPR) effect, have provided only modest survival benefits. This suboptimal outcome is likely due to physiolo...

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Bibliografiska uppgifter
Huvudupphovsmän: Wong, Cliff, Stylianopoulos, Triantafyllos, Cui, Jian, Martin, John, Chauhan, Vikash P., Jiang, Wen, Popović, Zoran, Jain, Rakesh K., Bawendi, Moungi G., Fukumura, Dai
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038705/
https://ncbi.nlm.nih.gov/pubmed/21245339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018382108
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