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Multistage nanoparticle delivery system for deep penetration into tumor tissue
Current Food and Drug Administration-approved cancer nanotherapeutics, which passively accumulate around leaky regions of the tumor vasculature because of an enhanced permeation and retention (EPR) effect, have provided only modest survival benefits. This suboptimal outcome is likely due to physiolo...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038705/ https://ncbi.nlm.nih.gov/pubmed/21245339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018382108 |
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