Multistage nanoparticle delivery system for deep penetration into tumor tissue

Current Food and Drug Administration-approved cancer nanotherapeutics, which passively accumulate around leaky regions of the tumor vasculature because of an enhanced permeation and retention (EPR) effect, have provided only modest survival benefits. This suboptimal outcome is likely due to physiolo...

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Bibliografische gegevens
Hoofdauteurs: Wong, Cliff, Stylianopoulos, Triantafyllos, Cui, Jian, Martin, John, Chauhan, Vikash P., Jiang, Wen, Popović, Zoran, Jain, Rakesh K., Bawendi, Moungi G., Fukumura, Dai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2011
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038705/
https://ncbi.nlm.nih.gov/pubmed/21245339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018382108
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