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Cationic Nanoparticles Have Superior Transvascular Flux into Solid Tumors: Insights from a Mathematical Model

Despite their great promise, only a few nanoparticle formulations have been approved for clinical use in oncology. The failure of nano-scale drugs to enhance cancer therapy is in large part due to inefficient delivery. To overcome this outstanding problem, a better understanding of how the physical...

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Detalhes bibliográficos
Main Authors: Stylianopoulos, Triantafyllos, Soteriou, Konstantinos, Fukumura, Dai, Jain, Rakesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3886728/
https://ncbi.nlm.nih.gov/pubmed/22855118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-012-0630-4
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