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Towards optimal design of cancer nanomedicines: Multi-stage nanoparticles for the treatment of solid tumors

Conventional drug delivery systems for solid tumors are composed of a nano-carrier that releases its therapeutic load. These two-stage nanoparticles utilize the Enhanced Permeability and Retention (EPR) effect to enable preferential delivery to tumor tissue. However, the size-dependency of the EPR,...

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Détails bibliographiques
Publié dans:Ann Biomed Eng
Auteurs principaux: Stylianopoulos, Triantafyllos, Economides, Eva-Athena, Baish, James W., Fukumura, Dai, Jain, Rakesh K.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519365/
https://ncbi.nlm.nih.gov/pubmed/25670323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-015-1276-9
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