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Combining two strategies to improve perfusion and drug delivery in solid tumors
Blood perfusion in tumors can be significantly lower than that in the surrounding normal tissue owing to the leakiness and/or compression of tumor blood vessels. Impaired perfusion reduces oxygen supply and results in a hypoxic microenvironment. Hypoxia promotes tumor progression and immunosuppressi...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832007/ https://ncbi.nlm.nih.gov/pubmed/24167277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318415110 |
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