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Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

Cancer and stromal cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing vascular perfusion. Tumour interstitial matrix also contributes to solid stress, with hyaluronan implicated as the primary matrix molecule responsible for vessel compression because...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chauhan, Vikash P., Martin, John D., Liu, Hao, Lacorre, Delphine A., Jain, Saloni R., Kozin, Sergey V., Stylianopoulos, Triantafyllos, Mousa, Ahmed S., Han, Xiaoxing, Adstamongkonkul, Pichet, Popović, Zoran, Huang, Peigen, Bawendi, Moungi G., Boucher, Yves, Jain, Rakesh K.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Pub. Group 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806395/
https://ncbi.nlm.nih.gov/pubmed/24084631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3516
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