Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

Cancer and stromal cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing vascular perfusion. Tumour interstitial matrix also contributes to solid stress, with hyaluronan implicated as the primary matrix molecule responsible for vessel compression because...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Chauhan, Vikash P., Martin, John D., Liu, Hao, Lacorre, Delphine A., Jain, Saloni R., Kozin, Sergey V., Stylianopoulos, Triantafyllos, Mousa, Ahmed S., Han, Xiaoxing, Adstamongkonkul, Pichet, Popović, Zoran, Huang, Peigen, Bawendi, Moungi G., Boucher, Yves, Jain, Rakesh K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2013
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806395/
https://ncbi.nlm.nih.gov/pubmed/24084631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3516
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge