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The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb

Overexpression of the oncogene MYBL2 (B-Myb) is associated with increased cell proliferation and serves as marker of poor prognosis in cancer. However, the mechanism by which B-Myb alters the cell cycle is not fully understood. In proliferating cells, B-Myb interacts with the MuvB core complex inclu...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Iness, Audra N., Felthousen, Jessica, Ananthapadmanabhan, Varsha, Sesay, Fatmata, Saini, Siddharth, Guiley, Keelan Z., Rubin, Seth M., Dozmorov, Mikhail, Litovchick, Larisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377300/
https://ncbi.nlm.nih.gov/pubmed/30206359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0490-y
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