The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb

Overexpression of the oncogene MYBL2 (B-Myb) is associated with increased cell proliferation and serves as marker of poor prognosis in cancer. However, the mechanism by which B-Myb alters the cell cycle is not fully understood. In proliferating cells, B-Myb interacts with the MuvB core complex inclu...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncogene
Hlavní autoři: Iness, Audra N., Felthousen, Jessica, Ananthapadmanabhan, Varsha, Sesay, Fatmata, Saini, Siddharth, Guiley, Keelan Z., Rubin, Seth M., Dozmorov, Mikhail, Litovchick, Larisa
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377300/
https://ncbi.nlm.nih.gov/pubmed/30206359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0490-y
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky