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The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb
Overexpression of the oncogene MYBL2 (B-Myb) is associated with increased cell proliferation and serves as marker of poor prognosis in cancer. However, the mechanism by which B-Myb alters the cell cycle is not fully understood. In proliferating cells, B-Myb interacts with the MuvB core complex inclu...
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| Veröffentlicht in: | Oncogene |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6377300/ https://ncbi.nlm.nih.gov/pubmed/30206359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0490-y |
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