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Restoring the DREAM Complex Inhibits the Proliferation of High-Risk HPV Positive Human Cells

SIMPLE SUMMARY: Human papillomaviruses are responsible for around 5% of all cancers, and to date there are no anti-viral therapeutics available for treating these cancers. In this report we demonstrate that in HPV positive cells the transcriptional repressor DREAM complex is disrupted by E7 proteins...

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Sonraí Bibleagrafaíochta
Foilsithe in:Cancers (Basel)
Main Authors: James, Claire D., Saini, Siddharth, Sesay, Fatmata, Ko, Kevin, Felthousen-Rusbasan, Jessica, Iness, Audra N., Nulton, Tara, Windle, Brad, Dozmorov, Mikhail G., Morgan, Iain M., Litovchick, Larisa
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866234/
https://ncbi.nlm.nih.gov/pubmed/33513914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030489
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